Viral infections: Certain viruses, such as hepatitis A, B, and C, can cause inflammation and damage to the liver.
Alcohol abuse: Heavy or prolonged alcohol use can cause liver damage and inflammation.
Obesity and metabolic disorders: Obesity, type 2 diabetes, and other metabolic disorders can cause fatty deposits to build up in the liver, leading to inflammation and scarring.
Autoimmune disorders: Autoimmune hepatitis, a disorder in which the immune system attacks the liver, can cause liver inflammation and damage.
Genetic conditions: Certain genetic conditions, such as hemochromatosis, Wilson's disease, and alpha-1 antitrypsin deficiency, can cause liver damage.
Medications and toxins: Certain medications, as well as exposure to certain toxins, can cause liver damage and inflammation.
Other medical conditions: Other medical conditions, such as chronic hepatitis B or C infection, nonalcoholic fatty liver disease, and cirrhosis, can also cause liver damage and inflammation.